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Recombinant Human INSL5/INSL7 Hybrid

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Recombinant Human INSL5/INSL7 Hybrid

商品详情参考文献相关资料

The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an insulin-like heterodimeric structure of two polypeptide chains held together by two inter-chain disulfide bonds. The INSL5/INSL7 hybrid contains the β-chain of INSL7 (Relaxin-3), linked to the α-chain of INSL5. The INSL5/INSL7 hybrid protein can specifically activate the G protein-coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant Human INSL5/INSL7 hybrid is a heterodimeric, 5.2 kDa protein consisting of a 27 amino acid β-chain linked to a 21 amino acid α-chain by two disulfide bonds.

Source: E.coli

Synonyms: None

AA Sequence: A-chain: QDLQTLCCTD GCSMTDLSAL C

B-chain: RAAPYGVRLC GREFIRAVIF TCGGSRW

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available

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