E-64D |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频下载地址入口

所在位置：首页 > 产品中心 > AGScientific > AGScientific产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

E-64D

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

咨询客服

立即购买加入购物车

CAS:88321-09-9Formula:C17H30N2O5MW:342.433Appearance:Solid

商品详情参考文献相关资料

An irreversible, highly selective cysteine protease inhibitor and cell permeable analog of E-64D. Specifically E-64D is an irreversible cathepsin L and B inhibitor.

Most recently e-64D, a pan-cysteine cathepsin inhibitor plays an important role in Ebola virus (EBOV) progression by preventing entry by filoviruses, especially EBOV. E-64d has been shown to lead to the accumulation of CTFs and AICD with no change in gamma and beta secretase activities. Additionally, utilizing E-64d has shown results in accumulation of autophagic bodies inside vacuoles in Arabidopsis root cells.

Additional Information

Synonyms	E-64D, E64d
Product #	E-2401
CAS #	88321-09-9
Formula	C₁₇ H₃₀ N₂ O₅
MW	342.433
Appearance	Solid
Solubility	Soluble in ethanol (>10 mg/ml), DMSO (20 mg/ml), DMF (30 mg/ml), and 1:1 DMSO:PBS (pH 7.2) (~0.5 mg/ml). Insoluble in water
Therapeutic Area	Neurological Disorders
Use	The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease by inhibiting cathepsin B, but not BACE1, β-secretase activity

Additional Information

MDL Number	MFCD00132883
ChemACX	X1061801-0
InChI	InChI=1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1
SMILES	CCOC(=O)[C@@H]1[C@H](O1)C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C

热销产品