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 Necrostatin-5 |产品详情|进口榴莲视频免费观看采购网





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    上海榴莲视频下载地址入口生物科技公司
    Tel:400-968-7988    021-33779008
    Necrostatin-5
    品牌:AG Scientific
    货号:
    规格:5 mg
    货期:

    CAS:337349-54-9Formula:C19H17N3O2S2MW:383.5Appearance:Whitetooff-whiteSolidPurity:98%(NMR)

    商品详情 参考文献 相关资料
    Inhibits non-apoptotic cell deathpathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1; partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5A.

    Additional Information

    SynonymsNec-5
    Product #N-1229
    CAS #337349-54-9
    Chemical Name3-p-MEthoxyphenyl-5,6-tetramethylenothieno[2,3-d] pyrimidin-4-one-2-mercaptoethylcyanide
    FormulaC19H17N3O2S2
    MW383.5
    AppearanceWhite to off-white Solid
    Purity98% (NMR)
    SolubilitySoluble in DMSO (10mg/ml)
    Storage Temp-20°C
    UseNecrostatin-5 is an inhibitor of necroptosis by indirect inhibition of RIP1 kinase

    Additional Information

    MDL NumberMFCD01448275
    ChemACXX1708411-0
    InChIInChI=1S/C19H17N3O2S2/c1-24-13-8-6-12(7-9-13)22-18(23)16-14-4-2-3-5-15(14)26-17(16)21-19(22)25-11-10-20/h6-9H,2-5,11H2,1H3
    SMILESCOc1ccc(cc1)n2c(=O)c3c4c(sc3nc2SCC#N)CCCC4
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