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An antioxidant and an inhibitor of NF-kB; prevents induction of nitric oxide synthase (NOS) by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells. Also inhibits breast cancer stem-like cells by blocking the NF-kB activity in MCF7 sphere and MCF7 cells.

Additional Information

Synonyms	Pyrrolidinedithiocarbamate Ammonium; PDC; APDC
Product #	P-2391
CAS #	5108-96-3
Chemical Name	Pyrrolidinedithiocarbamate Ammonium; PDC; APDC
Formula	C5H9NS2.NH3
MW	164.28
Appearance	White Solid
Purity	98%
Solubility	Soluble in DMSO (15 mg/ml) and H2O (1 mg/ml)
Storage Temp	+4°C
Therapeutic Area	Oncological Disorders
Use	An NF kappa B inhibitor.Induces apoptosis in smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells

Additional Information

MDL Number	MFCD00012720
ChemACX	X1002139-5
InChI	InChI=1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
SMILES	C1CCN(C1)C(=S)S.N