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    Anti-FANCA (phospho-S1149) Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-FANCA (phospho-S1149) Antibody
    商品详情 参考文献 相关资料
    Name: Anti-FANCA (phospho-S1149) Antibody
    See all FANCA primary antibodies
    Description: Rabbit polyclonal antibody to FANCA (phospho-S1149)
    Specificity: p-FANCA (S1149) pAb detects endogenous levels of FANCA protein only when phosphorylated at Ser1149.
    Applications: WB, IHC, ICC, IP
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthetic phosphopeptide derived from human FANCA around the phosphorylation site of Serine 1149.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 163 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
    Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
    Involvement in Disease: Fanconi anemia, complementation group A: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
    Post-Translational Modification: Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H.
    Cellular locations: Nucleus. Cytoplasm.

    The major form is nuclear. The minor form is cytoplasmic.
    Database Links:
  2. Entrez Gene: 2175?Human
  3. Entrez Gene: 14087?Mouse
  4. Omim: 607139?Human
  5. SwissProt: O15360?Human
  6. SwissProt: Q9JL70?Mouse
  7. Unigene: 290154?Human
    		8.
    Synonyms:
  8. FA Antibody
  9. FA 1 Antibody
  10. FA H Antibody
  11. FA1 Antibody
  12. FAA Antibody
  13. FACA Antibody
  14. FAH Antibody
  15. FANCA Antibody
  16. FANCA_HUMAN Antibody
  17. FANCH Antibody
  18. Fanconi anemia complementation group A Antibody
  19. Fanconi anemia complementation group H Antibody
  20. Fanconi anemia group A protein Antibody
  21. Fanconi anemia type 1 Antibody
  22. MGC75158 Antibody
  23. Protein FACA Antibody
    		24.
    Information: Target information shown above is from the UniProt Consortium.
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