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Anti-DVL2 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-DVL2 Antibody
    品牌：Antibodies
    货号：
    规格：100µl
    货期：

    Anti-DVL2 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-DVL2 Antibody
    See all DVL2 primary antibodies
    Description: Rabbit polyclonal antibody to DVL2
    Specificity: The antibody detects endogenous levels of total DVL2 protein.
    Applications: IHC
    Reactivity: Human, Mouse
    Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human dishevelled segment polarity protein 2
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antigen affinity purification.
    Concentration: 2.1mg / ml
    Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
    Storage: Store at -20?C
    Function: Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
    Sequence Similarities: Belongs to the DSH family.
    Post-Translational Modification: Phosphorylated by CSNK1D (PubMed:21422228, PubMed:9192851). WNT3A induces DVL2 phosphorylation by CSNK1E and MARK kinases (PubMed:25805136).
    Cellular locations: Cell membrane. Cytoplasm > Cytosol. Cytoplasmic vesicle. Nucleus.

    Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). Interaction with FOXK1 and FOXK2 induces nuclear translocations (PubMed:25805136).
    Database Links:
  2. Entrez Gene: 1856?Human
  3. Entrez Gene: 13543?Mouse
  4. Omim: 602151?Human
  5. SwissProt: O14641?Human
  6. SwissProt: Q60838?Mouse
  7. Unigene: 118640?Human
  8. Unigene: 5114?Mouse
    		9.
    Synonyms:
  9. Dishevelled 2 Antibody
  10. Dishevelled 2 (homologous to Drosophila dsh) Antibody
  11. Dishevelled dsh homolog 2 Antibody
  12. dishevelled segment polarity protein 2 Antibody
  13. Dishevelled-2 Antibody
  14. Dishevelled2 Antibody
  15. DSH homolog 2 Antibody
  16. DVL 2 Antibody
  17. Dvl2 Antibody
  18. DVL2_HUMAN Antibody
  19. Segment polarity protein dishevelled homolog DVL 2 Antibody
  20. Segment polarity protein dishevelled homolog DVL-2 Antibody
  21. Segment polarity protein dishevelled homolog DVL2 Antibody
    		22.
    Information: Target information shown above is from the UniProt Consortium.
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