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Anti-DIL-2 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-DIL-2 Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-DIL-2 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-DIL-2 Antibody
    See all DIL-2 primary antibodies
    Description: Rabbit polyclonal antibody to DIL-2
    Specificity: The antibody detects endogenous levels of total DIL-2 protein.
    Applications: WB, IHC
    Reactivity: Human, Mouse
    Immunogen: Synthesized peptide derived from internal of human DIL-2.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Concentration: 1.0mg / ml
    Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20?C
    Function: Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
    Tissue Specificity: Expressed in lung carcinoma cell lines but not in normal lung tissues.
    Sequence Similarities: Belongs to the TPX2 family.
    Cellular locations: Nucleus. Cytoplasm > Cytoskeleton > Spindle. Cytoplasm > Cytoskeleton > Spindle pole.

    During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.
    Database Links:
  2. Entrez Gene: 22974?Human
  3. Entrez Gene: 72119?Mouse
  4. Omim: 605917?Human
  5. SwissProt: Q9ULW0?Human
  6. SwissProt: A2APB8?Mouse
  7. Unigene: 244580?Human
  8. Unigene: 407737?Mouse
    		9.
    Synonyms:
  9. C20ORF1 Antibody
  10. C20orf2 Antibody
  11. Chromosome 20 Open Reading Frame 1 Antibody
  12. Differentially expressed in cancerous and non-cancerous lung cells 2 Antibody
  13. Differentially expressed in cancerous and noncancerous lung cells 2 Antibody
  14. Differentially expressed in lung cells Antibody
  15. Differentially expressed in lung cells 2 Antibody
  16. DIL 2 Antibody
  17. DIL-2 Antibody
  18. DIL2 Antibody
  19. FLS353 Antibody
  20. GD:C20orf1 Antibody
  21. HCA 519 Antibody
  22. HCA519 Antibody
  23. HCTP 4 Antibody
  24. HCTP4 Antibody
  25. Hepatocellular carcinoma associated antigen 519 Antibody
  26. Hepatocellular carcinoma-associated antigen 519 Antibody
  27. p100 Antibody
  28. Preferentially expressed in colorectal cancer Antibody
  29. Protein fls353 Antibody
  30. REPP 86 Antibody
  31. repp86 Antibody
  32. Restricted expression proliferation associated protein 100 Antibody
  33. Restricted expression proliferation-associated protein 100 Antibody
  34. Targeting protein for Xklp2 Antibody
  35. TPX 2 Antibody
  36. TPX2 Antibody
  37. TPX2 microtubule associated homolog Antibody
  38. TPX2 microtubule associated protein homolog Antibody
  39. TPX2 microtubule nucleation factor Antibody
  40. TPX2_HUMAN Antibody
    		41.
    Information: Target information shown above is from the UniProt Consortium.
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