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Anti-D-3-phosphoglycerate dehydrogenase Antibody

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Anti-D-3-phosphoglycerate dehydrogenase Antibody

品牌：Antibodies

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规格：100µl

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Anti-D-3-phosphoglycerate dehydrogenase Antibody

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Overview

Name:	Anti-D-3-phosphoglycerate dehydrogenase Antibody See all D-3-phosphoglycerate dehydrogenase primary antibodies
Description:	Rabbit polyclonal antibody to D-3-phosphoglycerate dehydrogenase
Specificity:	The antibody detects endogenous level of total D-3-phosphoglycerate dehydrogenase polyclonal antibody.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Recombinant human D-3-phosphoglycerate dehydrogenase protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Caprylic Acid Ammonium Sulfate Precipitation purified
Concentration:	1.0mg / mL
Formulation:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage:	Store at -20?C

Target

Function:	Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosesynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.
Involvement in Disease:	Phosphoglycerate dehydrogenase deficiency: An autosomal recessive inborn error of L-serine biosesynthesis, clinically characterized by congenital microcephaly, psychomotor retardation, and seizures. Neu-Laxova syndrome 1: A lethal, autosomal recessive multiple malformation syndrome characterized by ichthyosis, marked intrauterine growth restriction, microcephaly, short neck, limb deformities, hypoplastic lungs, edema, and central nervous system anomalies including lissencephaly, cerebellar hypoplasia and/or abnormal/agenesis of the corpus callosum. Abnormal facial features include severe proptosis with ectropion, hypertelorism, micrognathia, flattened nose, and malformed ears.
Sequence Similarities:	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Database Links:	Entrez Gene: 26227?Human Omim: 606879?Human SwissProt: O43175?Human Unigene: 487296?Human
Synonyms:	3 PGDH Antibody 3-PGDH Antibody 3-phosphoglycerate dehydrogenase Antibody 3PGDH Antibody D-3-phosphoglycerate dehydrogenase Antibody EC 1.1.1.95 Antibody Epididymis secretory protein Li 113 Antibody HEL S 113 Antibody NLS Antibody NLS1 Antibody PDG Antibody PGAD Antibody PGD Antibody PGDH Antibody PGDH3 Antibody PHGDH Antibody PHGDHD Antibody Phosphoglycerate dehydrogenase Antibody SERA Antibody SERA_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.