Anti-Csk Antibody |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频下载地址入口

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

Anti-Csk Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-Csk Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-Csk Antibody See all Csk primary antibodies
Description:	Mouse monoclonal antibody to Csk
Specificity:	This antibody detects endogenous levels of Csk and does not cross-react with related proteins.
Applications:	WB, ICC
Reactivity:	Human, Rat
Immunogen:	Recombinant full length Human Csk.
Host:	Mouse
Clonality:	Monoclonal
Conjugate:	Unconjugated
Molecular Weight:	Predicted band size:50KDa Observed band size:50KDa
Purity:	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Target

Function:	Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.
Tissue Specificity:	Expressed in lung and macrophages.
Sequence Similarities:	Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Post-Translational Modification:	Phosphorylated at Ser-364 by PKA, leading to increased activity. Autophosphorylated.
Cellular locations:	Cytoplasm. Cell membrane. Mainly cytoplasmic, also present in lipid rafts.
Database Links:	Entrez Gene: 1445 Human Entrez Gene: 315707 Rat Omim: 124095 Human SwissProt: P41240 Human SwissProt: P32577 Rat Unigene: 77793 Human Unigene: 2759 Rat
Synonyms:	C SRC Antibody C SRC kinase Antibody C src Tyrosine Kinase Antibody C-SRC kinase Antibody c-src tyrosine kinase Antibody CSK Antibody Csk A Antibody CSK_HUMAN Antibody CYTOPLASMIC TYROSINE KINASE Antibody EC 2.7.10.2 Antibody MGC112926 Antibody MGC117393 Antibody MGC154049 Antibody P60 Src Antibody Protein tyrosine kinase CYL Antibody Protein-tyrosine kinase CYL Antibody Proto oncogene tyrosine protein kinase Antibody Tyrosine protein kinase CSK Antibody Tyrosine-protein kinase CSK Antibody zgc:154049 Antibody
Information:	Target information shown above is from the UniProt Consortium.