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Anti-CD95 Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-CD95 Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-CD95 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-CD95 Antibody
    See all CD95 primary antibodies
    Description: Rabbit polyclonal antibody to CD95
    Specificity: CD95 Polyclonal Antibody detects endogenous levels of CD95 protein.
    Applications: WB, IHC, ELISA
    Reactivity: Human
    Immunogen: Synthesized peptide derived from the C-terminal region of human CD95.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Concentration: 1mg / ml
    Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    Storage: Store at -20?C / 1 year
    Function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
    Tissue Specificity: Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6.
    Involvement in Disease: Autoimmune lymphoproliferative syndrome 1A: A disorder of apoptosis that manifests in early childhood and results in the accumulation of autoreactive lymphocytes. It is characterized by non-malignant lymphadenopathy with hepatosplenomegaly, and autoimmune hemolytic anemia, thrombocytopenia and neutropenia.
    Post-Translational Modification: N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
    Cellular locations: Cell membrane.
    Database Links:
  1. Entrez Gene: 355?Human
  2. Omim: 134637?Human
  3. SwissProt: P25445?Human
  4. Unigene: 244139?Human
  5. Synonyms:
  6. ALPS 1A Antibody
  7. ALPS1A Antibody
  8. APO 1 Antibody
  9. Apo 1 antigen Antibody
  10. APO 1 cell surface antigen Antibody
  11. Apo-1 antigen Antibody
  12. APO1 Antibody
  13. Apo1 antigen Antibody
  14. APO1 cell surface antigen Antibody
  15. Apoptosis antigen 1 Antibody
  16. Apoptosis mediating surface antigen FAS Antibody
  17. Apoptosis-mediating surface antigen FAS Antibody
  18. APT 1 Antibody
  19. APT1 Antibody
  20. CD 95 Antibody
  21. CD 95 antigen Antibody
  22. CD95 Antibody
  23. CD95 antigen Antibody
  24. Delta Fas Antibody
  25. Delta Fas/APO 1/CD95 Antibody
  26. Delta Fas/APO1/CD95 Antibody
  27. Fas Antibody
  28. Fas (TNF receptor superfamily, member 6) Antibody
  29. FAS 1 Antibody
  30. FAS 827dupA Antibody
  31. Fas AMA Antibody
  32. FAS Antigen Antibody
  33. Fas cell surface death receptor Antibody
  34. FAS1 Antibody
  35. FASLG receptor Antibody
  36. FASTM Antibody
  37. sFAS Antibody
  38. Surface antigen APO1 Antibody
  39. TNF receptor superfamily, member 6 Antibody
  40. TNFRSF 6 Antibody
  41. TNFRSF6 Antibody
  42. TNR6_HUMAN Antibody
  43. Tumor necrosis factor receptor superfamily member 6 Antibody
  44. Information: Target information shown above is from the UniProt Consortium.
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