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Anti-WDR77 Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-WDR77 Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-WDR77 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-WDR77 Antibody
    See all WDR77 primary antibodies
    Description: Mouse monoclonal antibody to WDR77.
    Applications: WB, ICC
    Dilutions: WB: 1:500 - 1:2000, ICC: 1:50 - 1:200.
    Reactivity: Human
    Immunogen: Recombinant protein of human WDR77.
    Host: Mouse
    Clonality: Monoclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
    Tissue Specificity: Highly expressed in heart, skeletal muscle, spleen, testis, uterus, prostate and thymus. In testis, expressed in germ cells and Leydig cells, but not in peritubular myocytes, nor in Sertoli cells. Expressed in prostate cancers, in seminomas and in Leydig cell tumors.
    Cellular locations: Nucleus. Cytoplasm.

    Nuclear in Leydig cells and cytoplasmic in germ cells during fetal testicular development. In ***** testis, predominantly nuclear. Subcellular locations varies from nuclear to cytoplasmic in various tumors.
    Database Links:
  1. Entrez Gene: 79084 Human
  2. Omim: 611734 Human
  3. SwissProt: Q9BQA1 Human
  4. Unigene: 204773 Human
  5. Synonyms:
  6. 2610312E17Rik Antibody
  7. Androgen receptor cofactor p44 Antibody
  8. C79984 Antibody
  9. HKMT1069 Antibody
  10. MEP 50 Antibody
  11. MEP-50 Antibody
  12. MEP50 Antibody
  13. MEP50_HUMAN Antibody
  14. Methylosome protein 50 Antibody
  15. MGC2722 Antibody
  16. Nbla10071 Antibody
  17. p44 Antibody
  18. p44/Mep50 Antibody
  19. RGD1310479 Antibody
  20. RP11 552M11.3 Antibody
  21. WD repeat containing protein 77 Antibody
  22. WD repeat domain 77 Antibody
  23. WD repeat-containing protein 77 Antibody
  24. WDR77 Antibody
  25. Information: Target information shown above is from the UniProt Consortium.
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