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Anti-HDAC9 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-HDAC9 Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-HDAC9 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-HDAC9 Antibody
    See all HDAC9 primary antibodies
    Description: Rabbit polyclonal antibody to HDAC9
    Specificity: HDAC9 pAb detects endogenous levels of HDAC9 protein.
    Applications: WB
    Reactivity: Human, Mouse, Rat
    Immunogen: A synthetic peptide corresponding to residues in Human HDAC9 .
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 117 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.6.
    Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.
    Tissue Specificity: Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level).
    Sequence Similarities: Belongs to the histone deacetylase family. HD type 2 subfamily.
    Post-Translational Modification: Phosphorylated on Ser-220 and Ser-450; which promotes 14-3-3-binding, impairs interaction with MEF2, and antagonizes antimyogenic activity. Phosphorylated on Ser-240; which impairs nuclear accumulation (By similarity). Isoform 7 is phosphorylated on Tyr-1010. Phosphorylated by the PKC kinases PKN1 and PKN2, impairing nuclear import.
    Cellular locations: Nucleus.
    Database Links:
  2. Entrez Gene: 9734 Human
  3. Entrez Gene: 687001 Rat
  4. Omim: 606543 Human
  5. SwissProt: Q9UKV0 Human
  6. Unigene: 196054 Human
    		7.
    Synonyms:
  7. HD 7 Antibody
  8. HD 7B Antibody
  9. HD 9 Antibody
  10. HD7 Antibody
  11. HD7B Antibody
  12. HD9 Antibody
  13. HDAC Antibody
  14. HDAC 7 Antibody
  15. HDAC 7B Antibody
  16. HDAC 9 Antibody
  17. HDAC 9B Antibody
  18. HDAC 9FL Antibody
  19. HDAC7 Antibody
  20. HDAC7B Antibody
  21. HDAC9 Antibody
  22. HDAC9B Antibody
  23. HDAC9FL Antibody
  24. HDAC9_HUMAN Antibody
  25. HDRP Antibody
  26. Histone deacetylase 4/5 related protein Antibody
  27. Histone deacetylase 7 Antibody
  28. Histone deacetylase 7B Antibody
  29. Histone deacetylase 9 Antibody
  30. Histone deacetylase 9A Antibody
  31. Histone deacetylase related protein Antibody
  32. Histone deacetylase-related protein Antibody
  33. KIAA0744 Antibody
  34. MEF2 interacting transcription repressor MITR Antibody
  35. MEF2 interacting transcription repressor protein Antibody
  36. MEF2-interacting transcription repressor MITR Antibody
  37. MITR Antibody
    		38.
    Information: Target information shown above is from the UniProt Consortium.
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