Warning: mkdir(): No space left on device in /www/wwwroot/zhenghe1718.com/func.php on line 127

Warning: file_put_contents(./cachefile_yuan/99dujia.com/cache/86/3bd44/0f65e.html): failed to open stream: No such file or directory in /www/wwwroot/zhenghe1718.com/func.php on line 115
Anti-SEK1 / MKK4 (Phospho-Thr261) Antibody |产品详情|进口榴莲视频免费观看采购网


    榴莲视频下载地址入口,8008APP幸福宝榴莲,榴莲视频免费观看,榴莲视频污污污下载

    订购信息
    上海榴莲视频下载地址入口生物科技公司
    Tel:400-968-7988    021-33779008
    Anti-SEK1 / MKK4 (Phospho-Thr261) Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-SEK1 / MKK4 (Phospho-Thr261) Antibody
    商品详情 参考文献 相关资料
    Name: Anti-SEK1 / MKK4 (Phospho-Thr261) Antibody
    See all SEK1 primary antibodies
    Description: Rabbit polyclonal antibody to SEK1 / MKK4 (Phospho-Thr261)
    Specificity: The antibody detects endogenous level of SEK1 / MKK4 only when phosphorylated at threonine 261.
    Applications: IHC, IF
    Reactivity: Human, Mouse, Rat
    Immunogen: Peptide sequence around phosphorylation site of threonine261 (A-K-T(p)-RD) derived from Human SEK1 / MKK4.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
    Concentration: 1.0mg / ml
    Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
    Function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of the Thr residue by MAP2K7/MKK7 seems to be the prerequisite for JNK activation at least in response to proinflammatory cytokines, while other stimuli activate both MAP2K4/MKK4 and MAP2K7/MKK7 which synergistically phosphorylate JNKs. MAP2K4 is required for maintaining peripheral lymphoid homeostasis. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Whereas MAP2K7/MKK7 exclusively activates JNKs, MAP2K4/MKK4 additionally activates the p38 MAPKs MAPK11, MAPK12, MAPK13 and MAPK14.
    Tissue Specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
    Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Post-Translational Modification: Activated by phosphorylation on Ser-257 and Thr-261 by MAP kinase kinase kinases (MAP3Ks).
    Cellular locations: Cytoplasm. Nucleus.
    Database Links:
  2. Entrez Gene: 6416?Human
  3. Entrez Gene: 26398?Mouse
  4. Entrez Gene: 287398?Rat
  5. Omim: 601335?Human
  6. SwissProt: P45985?Human
  7. SwissProt: P47809?Mouse
  8. Unigene: 514681?Human
  9. Unigene: 412922?Mouse
    		10.
    Synonyms:
  10. c Jun N terminal kinase kinase 1 Antibody
  11. C-JUN N-terminal kinase kinase 1 Antibody
  12. Dual specificity mitogen activated protein kinase kinase 4 Antibody
  13. Dual specificity mitogen-activated protein kinase kinase 4 Antibody
  14. JNK Activated Kinase 1 Antibody
  15. JNK activating kinase 1 Antibody
  16. JNK-activating kinase 1 Antibody
  17. JNKK Antibody
  18. JNKK1 Antibody
  19. MAP kinase kinase 4 Antibody
  20. Map2k4 Antibody
  21. MAPK ERK kinase 4 Antibody
  22. MAPK/ERK kinase 4 Antibody
  23. MAPKK 4 Antibody
  24. MAPKK4 Antibody
  25. MEK 4 Antibody
  26. MEK4 Antibody
  27. Mitogen activated protein kinase kinase 4 Antibody
  28. MKK 4 Antibody
  29. MKK4 Antibody
  30. MP2K4_HUMAN Antibody
  31. PRKMK4 Antibody
  32. SAPK ERK kinase 1 Antibody
  33. SAPK/ERK kinase 1 Antibody
  34. SAPKK 1 Antibody
  35. SAPKK1 Antibody
  36. SEK1 Antibody
  37. SERK1 Antibody
  38. SKK1 Antibody
  39. Stress activated protein kinase kinase 1 Antibody
    		40.
    Information: Target information shown above is from the UniProt Consortium.
    • 关于榴莲视频下载地址入口
    • 购物流程
    • 支付方式
    • 配送方式
    Copyright@ 2003-2026  进口榴莲视频免费观看采购网版权所有     

    BIOLEAF热搜   BIOLEAF8008APP幸福宝榴莲   BIOLEAF ELISA   BIOLEAF榴莲视频免费观看   BIOLEAF品牌   BIOLEAF抗体   BIOLEAF耗材   BIOLEAF小仪器

    sitemap   细胞库查询   危险品图标

    本公司网站所展示销售的产品仅供科研！

             沪ICP备08023583号-6     
    产品咨询
    QQ扫码沟通
    在线客服
    服务电话
    400-968-7988
    扫码关注
    微信公众号二维码

    沪公网安备 31011202007338号
    网站地图