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 Anti-TIMP-1 (G94) Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-TIMP-1 (G94) Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-TIMP-1 (G94) Antibody

    商品详情 参考文献 相关资料
    Name: Anti-TIMP-1 (G94) Antibody
    See all TIMP-1 primary antibodies
    Description: Rabbit polyclonal antibody to TIMP-1 (G94)
    Specificity: TIMP-1 (G94) pAb detects endogenous levels of TIMP-1 protein.
    Applications: WB
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthetic peptide, corresponding to amino acids 61-110 of Human TIMP-1.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 23 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
    Function: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
    Tissue Specificity: Detected in rheumatoid synovial fluid (at protein level).
    Sequence Similarities: Belongs to the protease inhibitor I35 (TIMP) family.
    Post-Translational Modification: The activity of TIMP1 is dependent on the presence of disulfide bonds.
    Cellular locations: Secreted.
    Database Links:
  1. Entrez Gene: 7076 Human
  2. Entrez Gene: 21857 Mouse
  3. Entrez Gene: 116510 Rat
  4. Omim: 305370 Human
  5. SwissProt: P01033 Human
  6. SwissProt: P12032 Mouse
  7. SwissProt: P30120 Rat
  8. Unigene: 522632 Human
  9. Unigene: 8245 Mouse
  10. Unigene: 25754 Rat
  11. Synonyms:
  12. Clgi Antibody
  13. Collagenase inhibitor Antibody
  14. Collagenase inhibitor, Human Antibody
  15. EPA Antibody
  16. EPO Antibody
  17. Erythroid Potentiating Activity Antibody
  18. Erythroid-potentiating activity Antibody
  19. Fibroblast collagenase inhibitor Antibody
  20. FLJ90373 Antibody
  21. HCI Antibody
  22. Human Collagenase Inhibitor Antibody
  23. Metalloproteinase inhibitor 1 Antibody
  24. Metalloproteinase inhibitor 1 precursor Antibody
  25. OTTHUMP00000023214 Antibody
  26. TIMP Antibody
  27. TIMP 1 Antibody
  28. TIMP metallopeptidase inhibitor 1 Antibody
  29. TIMP-1 Antibody
  30. TIMP1 Antibody
  31. TIMP1 protein Antibody
  32. TIMP1_HUMAN Antibody
  33. Tissue Inhibitor of Metalloproteinase 1 Antibody
  34. Tissue inhibitor of metalloproteinases Antibody
  35. Tissue inhibitor of metalloproteinases 1 Antibody
  36. Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor Antibody
  37. Information: Target information shown above is from the UniProt Consortium.
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