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Anti-HLA G Antibody

品牌：Antibodies

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规格：100µg

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Anti-HLA G Antibody

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Name:	Anti-HLA G Antibody See all HLA G primary antibodies
Description:	Mouse monoclonal (87G) antibody to HLA G.
Specificity:	The antibody 87G recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells. The antibody 87G blocks interaction of HLA-G with inhibitory receptors.
Applications:	FC, IHC-Fr, ELISA, FUNC
Reactivity:	Human
Immunogen:	HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.
Host:	Mouse
Clonality:	Monoclonal
Clone:	87G
Isotype:	IgG2a
Conjugate:	Unconjugated
Purification:	Protein A chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 μm filter sterilised). Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
Storage:	Store at 2-8°C.

Function:	Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Tissue Specificity:	Expressed in trophoblasts.
Sequence Similarities:	Belongs to the MHC class I family.
Cellular locations:	Membrane.
Database Links:	Entrez Gene: 3135?Human Omim: 142871?Human SwissProt: P17693?Human Unigene: 512152?Human
Synonyms:	B2 microglobulin Antibody DADB-15K14.8 Antibody HLA 6.0 Antibody HLA class I histocompatibility antigen alpha chain G Antibody HLA class I histocompatibility antigen, alpha chain G Antibody HLA class I molecule Antibody HLA G Antibody HLA G antigen Antibody HLA G histocompatibility antigen class I G Antibody HLA G3 Antibody HLA-G Antibody HLA-G histocompatibility antigen, class I Antibody HLA60 Antibody HLAG Antibody HLAG_HUMAN Antibody Major histocompatibility complex class I G Antibody MHC class I antigen Antibody MHC class I antigen G Antibody MHC G Antibody T-cell A locus Antibody TCA Antibody
Information:	Target information shown above is from the UniProt Consortium.