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Anti-NOS1 Antibody

品牌：Antibodies

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规格：100µg

货期：

应用：

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Anti-NOS1 Antibody

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Overview

Name:	Anti-NOS1 Antibody See all nNOS (neuronal) primary antibodies
Description:	Goat polyclonal antibody to NOS1.
Applications:	ELISA, WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human NOS1 (C terminal).
Sequence:	C-ESKKDTDEVFSS
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Tissue Specificity:	Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
Sequence Similarities:	Belongs to the NOS family.
Post-Translational Modification:	Ubiquitinated; mediated by STUB1/CHIP in the presence of Hsp70 and Hsp40 (in vitro).
Cellular locations:	Cell membrane > Sarcolemma. Cell projection > Dendritic spine. In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).
Database Links:	Entrez Gene: 4842?Human Omim: 163731?Human SwissProt: P29475?Human Unigene: 654410?Human Unigene: 684465?Human Unigene: 684466?Human Unigene: 684467?Human
Synonyms:	2310005C01Rik Antibody BNOS Antibody Constitutive NOS Antibody EC 1.14.13.39 Antibody IHPS 1 Antibody IHPS1 Antibody N-NOS Antibody NC-NOS Antibody neuronal Nitric Oxide Synthase Antibody Neuronal NOS Antibody Nitric oxide synthase , neuronal, included Antibody Nitric oxide synthase 1 Antibody Nitric oxide synthase 1 (neuronal) Antibody Nitric oxide synthase, brain Antibody Nitric oxide synthase, penile neuronal, included Antibody NNOS Antibody nNOS (neuronal) Antibody NO Antibody NOS Antibody NOS 1 Antibody NOS type I Antibody NOS-I Antibody NOS1 Antibody NOS1_HUMAN Antibody Peptidyl-cysteine S-nitrosylase NOS1 Antibody
Information:	Target information shown above is from the UniProt Consortium.