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Anti-CD11b Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-CD11b Antibody
    品牌：Antibodies
    货号：
    规格：100µg
    货期：

    Anti-CD11b Antibody
    商品详情 参考文献 相关资料
    Name: Anti-CD11b Antibody
    See all CD11b primary antibodies
    Description: Rat monoclonal (M1/70) antibody to CD11b.
    Specificity: The rat monoclonal antibody M1/70 detects CD11b (integrin alphaM subunit), a type I transmembrane protein mainly expressed on monocytes/macrophages, granulocytes and NK-cells, which associates with CD18 to form Mac-1 integrin that plays important role in cell-cell interactions.
    Applications: FC, IP, IHC-Fr, FUNC
    Reactivity: Human, Non-Human Primates, Mouse, Rabbit
    Immunogen: B10 mouse spleen cells enriched for T cells.
    Host: Rat
    Clonality: Monoclonal
    Clone: M1/70
    Isotype: IgG2b
    Conjugate: Unconjugated
    Purification: Protein G chromatography.
    Concentration: 1 mg/ml
    Purity: > 95% (by SDS-PAGE)
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.4, without Azide (0.2 μm filter sterilised). Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
    Storage: Store at 2-8°C.
    Function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration (PubMed:8986723, PubMed:9382884, PubMed:9862668). In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (By similarity). May regulate phagocytosis-induced apoptosis in extravasated neutrophils (PubMed:8986723). May play a role in mast cell development (PubMed:9862668).
    Tissue Specificity: Predominantly expressed in monocytes and granulocytes (PubMed:3887182, PubMed:8986723). Expressed in a subset of peritoneal mast cells (PubMed:9862668).
    Sequence Similarities: Belongs to the integrin alpha chain family.
    Cellular locations: Cell membrane. Membrane raft.
    Database Links:
  2. Entrez Gene: 3684?Human
  3. Entrez Gene: 16409?Mouse
  4. Entrez Gene: 100351865?Rabbit
  5. Omim: 120980?Human
  6. SwissProt: P11215?Human
  7. SwissProt: P05555?Mouse
  8. Unigene: 172631?Human
  9. Unigene: 262106?Mouse
    		10.
    Synonyms:
  10. antigen CD11b (p170) Antibody
  11. Antigen CD11b p170 Antibody
  12. CD11 antigen like family member B Antibody
  13. CD11 antigen-like family member B Antibody
  14. CD11b Antibody
  15. CD11b/CD18 Antibody
  16. CD49d Antibody
  17. Cell surface glycoprotein MAC-1 subunit alpha Antibody
  18. Complement component 3 receptor 3 subunit Antibody
  19. Complement Component Receptor 3 Alpha Antibody
  20. Complement receptor type 3, alpha subunit Antibody
  21. CR 3 alpha chain Antibody
  22. CR 3 alpha chain (CR3A) Antibody
  23. CR-3 alpha chain Antibody
  24. CR3 Antibody
  25. CR3A Antibody
  26. F730045J24Rik Antibody
  27. Integrin Alpha M Antibody
  28. Integrin alpha M chain Antibody
  29. Integrin alpha-M Antibody
  30. Integrin beta 2 alpha subunit Antibody
  31. Integrin subunit alpha M Antibody
  32. integrin, alpha M (complement component 3 receptor 3 subunit) Antibody
  33. ITAM_HUMAN Antibody
  34. ITGAM Antibody
  35. Leukocyte adhesion receptor MO1 Antibody
  36. Ly-40 Antibody
  37. MAC 1 Antibody
  38. Mac-1a Antibody
  39. MAC1 Antibody
  40. Mac1, alpha subunit Antibody
  41. MAC1A Antibody
  42. Macrophage antigen alpha polypeptide Antibody
  43. MGC117044 Antibody
  44. Mo1, alpha subunit Antibody
  45. MO1A Antibody
  46. Neutrophil adherence receptor Antibody
  47. Neutrophil adherence receptor alpha M subunit Antibody
  48. SLEB6 Antibody
    		49.
    Information: Target information shown above is from the UniProt Consortium.
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