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Anti-FOXL2 Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-FOXL2 Antibody
    品牌:Antibodies
    货号:
    规格:100µg
    货期:

    Anti-FOXL2 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-FOXL2 Antibody
    See all FOXL2 primary antibodies
    Description: Goat polyclonal antibody to FOXL2.
    Applications: ELISA, WB, IHC
    Reactivity: Human, Mouse
    Immunogen: Synthetic peptide corresponding to Human FOXL2 (C terminal).
    Sequence: C-DSKTGALHSRLDL
    Host: Goat
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Concentration: 100 μg at 0.5 mg/ml.
    Product Form: Liquid
    Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. Is a regulator of CYP19 expression. Is a transcriptional repressor of STAR. Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element.
    Tissue Specificity: Expressed in the mesenchyme of developing eyelids. Expressed in ovaries throughout development and *****hood, localized to the undifferentiated granulosa cells in small and medium follicles as well as cumulus cells of preovulatory follicles. Expressed in the pituitary.
    Post-Translational Modification: Sumoylated with SUMO1; sumoylation is required for transcriptional repression activity.
    Cellular locations: Nucleus.
    Database Links:
  1. Entrez Gene: 668?Human
  2. Entrez Gene: 26927?Mouse
  3. Omim: 605597?Human
  4. SwissProt: P58012?Human
  5. SwissProt: O88470?Mouse
  6. Unigene: 289292?Human
  7. Unigene: 151239?Mouse
  8. Synonyms:
  9. Blepharophimosis Antibody
  10. Blepharophimosis epicanthus inversus and ptosis Antibody
  11. Blepharophimosis epicanthus inversus and ptosis 1 Antibody
  12. BPES Antibody
  13. BPES 1 Antibody
  14. BPES1 Antibody
  15. Epicanthus inversus and ptosis 1 Antibody
  16. Forkhead box L2 Antibody
  17. Forkhead box protein L2 Antibody
  18. Forkhead transcription factor FOXL2 Antibody
  19. FOX L2 Antibody
  20. FOXL 2 Antibody
  21. FOXL2 Antibody
  22. FOXL2_HUMAN Antibody
  23. PFRK Antibody
  24. PINTO Antibody
  25. PITUITARY FORKHEAD FACTOR Antibody
  26. POF 3 Antibody
  27. POF3 Antibody
  28. Information: Target information shown above is from the UniProt Consortium.
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