Anti-Bax (S4) Antibody |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频下载地址入口

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

Anti-Bax (S4) Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-Bax (S4) Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-Bax (S4) Antibody See all Bax primary antibodies
Description:	Rabbit polyclonal antibody to Bax (S4)
Specificity:	Bax (S4) pAb detects endogenous levels of Bax protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to the N-terminus of Human Bax.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 21 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocations to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Tissue Specificity:	Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro-myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T-cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines.
Sequence Similarities:	Belongs to the Bcl-2 family.
Cellular locations:	Mitochondrion membrane. Cytoplasm. Colocalizes with 14-3-3 proteins in the cytoplasm. Under stress conditions, undergoes a conformation change that causes release from JNK-phosphorylated 14-3-3 proteins and translocations to the mitochondrion membrane.
Database Links:	Entrez Gene: 581?Human Entrez Gene: 12028?Mouse Entrez Gene: 24887?Rat Omim: 600040?Human SwissProt: Q07812?Human SwissProt: Q07813?Mouse SwissProt: Q63690?Rat Unigene: 624291?Human Unigene: 19904?Mouse Unigene: 10668?Rat
Synonyms:	Apoptosis regulator BAX Antibody Bax Antibody Bax-protein Antibody BAXA Antibody Baxdelta2G9 Antibody Baxdelta2G9omega Antibody Baxdelta2omega Antibody BAX_HUMAN Antibody Bcl-2-like protein 4 Antibody BCL2 associated X protein Antibody BCL2 associated X protein omega Antibody BCL2 associated X protein transcript variant delta2 Antibody Bcl2-L-4 Antibody BCL2L4 Antibody membrane isoform alpha Antibody
Information:	Target information shown above is from the UniProt Consortium.